UEHARA, Takeki: search on Z-Library

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1

Carryover effects of baloxavir acid in human nasopharyngeal/pharyngeal swabs on infectious titer testing of influenza virus

Baba, Keiko, Oka, Ryoko, Shano, Shinya, Omoto, Shinya, Noshi, Takeshi, Shishido, Takao, Naito, Akira, Kawaguchi, Keiko, Ishibashi, Toru, Uehara, Takeki

Journal:

Influenza and Other Respiratory Viruses

Year:

2020

Language:

english

File:

PDF, 437 KB

english, 2020

2

Baloxavir Marboxil for Prophylaxis against Influenza in Household Contacts

Ikematsu, Hideyuki, Hayden, Frederick G., Kawaguchi, Keiko, Kinoshita, Masahiro, de Jong, Menno D., Lee, Nelson, Takashima, Satoru, Noshi, Takeshi, Tsuchiya, Kenji, Uehara, Takeki

Journal:

New England Journal of Medicine

Year:

2020

File:

PDF, 624 KB

2020

3

Decrease in urinary creatinine in acute kidney injury influences diagnostic value of urinary biomarker-to-creatinine ratio in rats

Yutaka Tonomura, Takeki Uehara, Emi Yamamoto, Mikinori Torii, Mitsunobu Matsubara

Journal:

Year:

2011

Language:

english

File:

PDF, 730 KB

english, 2011

4

Cap-dependent Endonuclease Inhibitor S-033188 for the Treatment of Influenza: Results from a Phase 3, Randomized, Double-Blind, Placebo- and Active-Controlled Study in Otherwise Healthy Adolescents and Adults with Seasonal Influenza

Portsmouth, Simon, Kawaguchi, Keiko, Arai, Masatsugu, Tsuchiya, Kenji, Uehara, Takeki

Journal:

Open Forum Infectious Diseases

Year:

2017

Language:

english

File:

PDF, 185 KB

english, 2017

5

Predictive genomic biomarkers for drug-induced nephrotoxicity in mice

Kondo, Chiaki, Aoki, Miwa, Yamamoto, Emi, Tonomura, Yutaka, Ikeda, Minoru, Kaneto, Masako, Yamate, Jyoji, Torii, Mikinori, Uehara, Takeki

Journal:

The Journal of Toxicological Sciences

Year:

2012

Language:

english

File:

PDF, 930 KB

english, 2012

6

Genetic and epigenetic changes in fibrosis-associated hepatocarcinogenesis in mice

Chappell, Grace, Kutanzi, Kristy, Uehara, Takeki, Tryndyak, Volodymyr, Hong, Hue-Hua, Hoenerhoff, Mark, Beland, Frederick A., Rusyn, Ivan, Pogribny, Igor P.

Journal:

International Journal of Cancer

Year:

2014

Language:

english

File:

PDF, 682 KB

english, 2014

7

Comprehensive analysis of DNA methylation and gene expression of rat liver in a 2-stage hepatocarcinogenesis model

Omura, Ko, Uehara, Takeki, Morikawa, Yuji, Hayashi, Hitomi, Mitsumori, Kunitoshi, Minami, Keiichi, Kanki, Masayuki, Yamada, Hiroshi, Ono, Atsushi, Urushidani, Tetsuro

Journal:

The Journal of Toxicological Sciences

Year:

2014

Language:

english

File:

PDF, 3.21 MB

english, 2014

8

Baloxavir marboxil in Japanese patients with seasonal influenza: Dose response and virus type/subtype outcomes from a randomized phase 2 study

Watanabe, Akira, Ishida, Tadashi, Hirotsu, Nobuo, Kawaguchi, Keiko, Ishibashi, Toru, Shishido, Takao, Sato, Chisako, Portsmouth, Simon, Tsuchiya, Kenji, Uehara, Takeki

Journal:

Antiviral Research

Year:

2019

File:

PDF, 1.59 MB

2019

9

Prediction model of potential hepatocarcinogenicity of rat hepatocarcinogens using a large-scale toxicogenomics database

Takeki Uehara, Yohsuke Minowa, Yuji Morikawa, Chiaki Kondo, Toshiyuki Maruyama, Ikuo Kato, Noriyuki Nakatsu, Yoshinobu Igarashi, Atsushi Ono, Hitomi Hayashi, Kunitoshi Mitsumori, Hiroshi Yamada, Yasuo

Journal:

Toxicology and Applied Pharmacology

Year:

2011

Language:

english

File:

PDF, 1003 KB

english, 2011

10

miRNA expression atlas in male rat

Minami, Keiichi, Uehara, Takeki, Morikawa, Yuji, Omura, Ko, Kanki, Masayuki, Horinouchi, Akira, Ono, Atsushi, Yamada, Hiroshi, Ohno, Yasuo, Urushidani, Tetsuro

Journal:

Scientific Data

Year:

2014

Language:

english

File:

PDF, 1.60 MB

english, 2014

11

UTILIZATION OF A ONE-DIMENSIONAL SCORE FOR SURVEYING CHEMICAL-INDUCED CHANGES IN EXPRESSION LEVELS OF MULTIPLE BIOMARKER GENE SETS USING A LARGE-SCALE TOXICOGENOMICS DATABASE

KIYOSAWA, Naoki, SHIWAKU, Kouji, HIRODE, Mitsuhiro, OMURA, Ko, UEHARA, Takeki, SHIMIZU, Toshinobu, MIZUKAWA, Yumiko, MIYAGISHIMA, Toshikazu, ONO, Atsushi, NAGAO, Taku, URUSHIDANI, Tetsuro

Journal:

The Journal of Toxicological Sciences

Year:

2006

Language:

english

File:

PDF, 4.13 MB

english, 2006

12

Gene expression profiling of methapyrilene-induced hepatotoxicity in rat

Uehara, Takeki, Kiyosawa, Naoki, Hirode, Mitsuhiro, Omura, Ko, Shimizu, Toshinobu, Ono, Atsushi, Mizukawa, Yumiko, Miyagishima, Toshikazu, Nagao, Taku, Urushidani, Tetsuro

Journal:

The Journal of Toxicological Sciences

Year:

2008

Language:

english

File:

PDF, 27.04 MB

english, 2008

13

The Japanese toxicogenomics project: Application of toxicogenomics

Takeki Uehara, Atsushi Ono, Toshiyuki Maruyama, Ikuo Kato, Hiroshi Yamada, Yasuo Ohno, Tetsuro Urushidani

Journal:

Molecular Nutrition & Food Research

Year:

2010

Language:

english

File:

PDF, 329 KB

english, 2010

14

Characterization of copy number alterations in a mouse model of fibrosis-associated hepatocellular carcinoma reveals concordance with human disease

Chappell, Grace, Silva, Grace O., Uehara, Takeki, Pogribny, Igor P., Rusyn, Ivan

Journal:

Cancer Medicine

Year:

2016

Language:

english

File:

PDF, 524 KB

english, 2016

15

Utilization of CDKN1A/p21 gene for class discrimination of DNA damage-induced clastogenicity

Sakai, Rina, Kondo, Chiaki, Oka, Hiroyuki, Miyajima, Hirofumi, Kubo, Kihei, Uehara, Takeki

Journal:

Year:

2014

Language:

english

File:

PDF, 1.47 MB

english, 2014

16

Mechanistic roles of microRNAs in hepatocarcinogenesis: A study of thioacetamide with multiple doses and time-points of rats

Dweep, Harsh, Morikawa, Yuji, Gong, Binsheng, Yan, Jian, Liu, Zhichao, Chen, Tao, Bisgin, Halil, Zou, Wen, Hong, Huixiao, Shi, Tieliu, Gong, Ping, Castro, Christina, Uehara, Takeki, Wang, Yuping, Tong

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 3.47 MB

english, 2017

17

Characterization of influenza virus variants induced by treatment with the endonuclease inhibitor baloxavir marboxil

Omoto, Shinya, Speranzini, Valentina, Hashimoto, Takashi, Noshi, Takeshi, Yamaguchi, Hiroto, Kawai, Makoto, Kawaguchi, Keiko, Uehara, Takeki, Shishido, Takao, Naito, Akira, Cusack, Stephen

Journal:

Scientific Reports

Year:

2018

Language:

english

File:

PDF, 3.87 MB

english, 2018

18

Time course of the change and amelioration of nedaplatin-induced nephrotoxicity in rats

Takeki Uehara, Noriko Tsuchiya, Aki Masuda, Mikinori Torii, Masuhisa Nakamura, Jyoji Yamate, Toshiyuki Maruyama

Journal:

Journal of Applied Toxicology

Year:

2008

Language:

english

File:

PDF, 852 KB

english, 2008

19

Genomic biomarkers for cardiotoxicity in rats as a sensitive tool in preclinical studies

Nishimura, Yoko, Morikawa, Yuji, Kondo, Chiaki, Tonomura, Yutaka, Fukushima, Ryou, Torii, Mikinori, Uehara, Takeki

Journal:

Journal of Applied Toxicology

Year:

2013

Language:

english

File:

PDF, 667 KB

english, 2013

20

Comparative Nephrotoxicity of Cisplatin and Nedaplatin:Mechanisms and Histopathological Characteristics

Uehara, Takeki, Yamate, Jyoji, Torii, Mikinori, Maruyama, Toshiyuki

Journal:

Journal of Toxicologic Pathology

Year:

2011

Language:

english

File:

PDF, 404 KB

english, 2011

21

Baloxavir marboxil in Japanese pediatric patients with influenza: safety and clinical and virologic outcomes

Hirotsu, Nobuo, Sakaguchi, Hiroki, Sato, Chisako, Ishibashi, Toru, Baba, Keiko, Omoto, Shinya, Shishido, Takao, Tsuchiya, Kenji, Hayden, Frederick G, Uehara, Takeki, Watanabe, Akira

Journal:

Clinical Infectious Diseases

Year:

2019

Language:

english

File:

PDF, 941 KB

english, 2019

22

Identification of potential genomic biomarkers for early detection of chemically induced cardiotoxicity in rats

Yoko Mori, Chiaki Kondo, Yutaka Tonomura, Mikinori Torii, Takeki Uehara

Journal:

Year:

2010

Language:

english

File:

PDF, 1.34 MB

english, 2010

23

A toxicogenomic approach for identifying biomarkers for myelosuppressive anemia in rats

Takeki Uehara, Chiaki Kondo, Jyoji Yamate, Mikinori Torii, Toshiyuki Maruyama

Journal:

Year:

2011

Language:

english

File:

PDF, 364 KB

english, 2011

24

Comparative Analysis of the Relationship Between Trichloroethylene Metabolism and Tissue-Specific Toxicity Among Inbred Mouse Strains: Kidney Effects

Yoo, Hong Sik, Bradford, Blair U., Kosyk, Oksana, Uehara, Takeki, Shymonyak, Svitlana, Collins, Leonard B., Bodnar, Wanda M., Ball, Louise M., Gold, Avram, Rusyn, Ivan

Journal:

Journal of Toxicology and Environmental Health Part A

Year:

2015

Language:

english

File:

PDF, 655 KB

english, 2015

25

Plasma miR-208 as a useful biomarker for drug-induced cardiotoxicity in rats

Nishimura, Yoko, Kondo, Chiaki, Morikawa, Yuji, Tonomura, Yutaka, Torii, Mikinori, Yamate, Jyoji, Uehara, Takeki

Journal:

Journal of Applied Toxicology

Year:

2015

Language:

english

File:

PDF, 861 KB

english, 2015

26

LB16. Phase 3 Trial of Baloxavir Marboxil in High-Risk Influenza Patients (CAPSTONE-2 Study)

Ison, Michael G, Portsmouth, Simon, Yoshida, Yuki, Shishido, Takao, Hayden, Frederick, Uehara, Takeki

Journal:

Open Forum Infectious Diseases

Year:

2018

Language:

english

File:

PDF, 366 KB

english, 2018

27

Toxicogenomic multigene biomarker for predicting the future onset of proximal tubular injury in rats

Yohsuke Minowa, Chiaki Kondo, Takeki Uehara, Yuji Morikawa, Yasushi Okuno, Noriyuki Nakatsu, Atsushi Ono, Toshiyuki Maruyama, Ikuo Kato, Jyoji Yamate, Hiroshi Yamada, Yasuo Ohno, Tetsuro Urushidani

Journal:

Year:

2012

Language:

english

File:

PDF, 1.01 MB

english, 2012

28

Acetaminophen-induced acute liver injury in HCV transgenic mice

Uehara, Takeki, Kosyk, Oksana, Jeannot, Emmanuelle, Bradford, Blair U., Tech, Katherine, Macdonald, Jeffrey M., Boorman, Gary A., Chatterjee, Saurabh, Mason, Ronald P., Melnyk, Stepan B., Tryndyak, Vo

Journal:

Toxicology and Applied Pharmacology

Year:

2013

Language:

english

File:

PDF, 1.51 MB

english, 2013

29

Combinatorial Measurement of CDKN1A/p21 and KIF20A Expression for Discrimination of DNA Damage-Induced Clastogenicity

Sakai, Rina, Morikawa, Yuji, Kondo, Chiaki, Oka, Hiroyuki, Miyajima, Hirofumi, Kubo, Kihei, Uehara, Takeki

Journal:

International Journal of Molecular Sciences

Year:

2014

Language:

english

File:

PDF, 1.76 MB

english, 2014

30

Toxicogenomics discrimination of potential hepatocarcinogenicity of non-genotoxic compounds in rat liver

Fumihiro Yamada, Kayo Sumida, Takeki Uehara, Yuji Morikawa, Hiroshi Yamada, Tetsuro Urushidani, Yasuo Ohno

Journal:

Journal of Applied Toxicology

Year:

2012

Language:

english

File:

PDF, 1.90 MB

english, 2012

31

Protein Plug in the Pancreatic Duct Mimicking Pancreatic Adenocarcinoma

Yamaguchi, Takeru, Kadowaki, Yoshihiko, Okino, Takeshi, Uehara, Eriko, Ohmori, Mika, Mori, Takeki

Journal:

ACG Case Reports Journal

Year:

2019

File:

PDF, 356 KB

2019

32

Comment to: Baloxavir efficacy in North American Adults

Portsmouth, Simon, Kawaguchi, Keiko, Uehara, Takeki, Hayden, Frederick G.

Journal:

European Journal of Internal Medicine

Year:

2020

File:

PDF, 401 KB

2020

33

A toxicogenomics approach for risk assessment of glutathione depletion and oxidative stress-induced nongenotoxic hepatocarcinogenesis in the rat liver

Takeki Uehara, Naoki Kiyosawa, Atsushi Ono, Toshikazu Miyagishima, Tetsuro Urushidani, Taku Nagao

Journal:

Toxicology Letters

Year:

2006

Language:

english

File:

PDF, 83 KB

english, 2006

34

Boorman's Pathology of the Rat || Esophagus and Stomach

Year:

2018

Language:

english

File:

PDF, 16.35 MB

english, 2018

35

Nephrotoxicity of a novel antineoplastic platinum complex, nedaplatin: a comparative study with cisplatin in rats

Takeki Uehara, Hiroshi Watanabe, Fumio Itoh, Satoshi Inoue, Hikaru Koshida, Masuhisa Nakamura, Jyoji Yamate, Toshiyuki Maruyama

Journal:

Archives of Toxicology

Year:

2005

Language:

english

File:

PDF, 604 KB

english, 2005

36

Predicting Drug-Induced Hepatotoxicity Using QSAR and Toxicogenomics Approaches

Low, Yen, Uehara, Takeki, Minowa, Yohsuke, Yamada, Hiroshi, Ohno, Yasuo, Urushidani, Tetsuro, Sedykh, Alexander, Muratov, Eugene, Kuz’min, Viktor, Fourches, Denis, Zhu, Hao, Rusyn, Ivan, Tropsha, Alex

Journal:

Chemical Research in Toxicology

Year:

2011

Language:

english

File:

PDF, 4.41 MB

english, 2011

37

GENE EXPRESSION PROFILING OF RAT LIVER TREATED WITH SERUM TRIGLYCERIDE-DECREASING COMPOUNDS

OMURA, Ko, KIYOSAWA, Naoki, UEHARA, Takeki, HIRODE, Mitsuhiro, SHIMIZU, Toshinobu, MIYAGISHIMA, Toshikazu, ONO, Atsushi, NAGAO, Taku, URUSHIDANI, Tetsuro

Journal:

The Journal of Toxicological Sciences

Year:

2007

Language:

english

File:

PDF, 1.22 MB

english, 2007

38

Heterogeneous Liver Lobe Responses of Carbon Tetrachloride-Induced Hepatotoxicity in Male Rats Pretreated with Hepatic Enzyme-Inducing Agents

Uehara, Takeki, Murai, Takashi, Inoue, Satoshi, Maruyama, Toshiyuki, Touchi, Akira, Mori, Satoru, Matsubara, Takashi

Journal:

Journal of Toxicologic Pathology

Year:

2004

File:

PDF, 736 KB

2004

39

A toxicogenomics approach for early assessment of potential non-genotoxic hepatocarcinogenicity of chemicals in rats

Takeki Uehara, Mitsuhiro Hirode, Atsushi Ono, Naoki Kiyosawa, Ko Omura, Toshinobu Shimizu, Yumiko Mizukawa, Toshikazu Miyagishima, Taku Nagao, Tetsuro Urushidani

Journal:

Year:

2008

Language:

english

File:

PDF, 1.95 MB

english, 2008

40

Evaluation of the usefulness of biomarkers for cardiac and skeletal myotoxicity in rats

Yutaka Tonomura, Yoko Mori, Mikinori Torii, Takeki Uehara

Journal:

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

41

Histopathological and molecular signatures of a mouse model of acute-on-chronic alcoholic liver injury demonstrate concordance with human alcoholic hepatitis

Furuya, Shinji, Cichocki, Joseph A, Konganti, Kranti, Dreval, Kostiantyn, Uehara, Takeki, Katou, Yuuki, Fukushima, Hisataka, Kono, Hiroshi, Pogribny, Igor P, Argemi, Josepmaria, Bataller, Ramon, Rusyn

Journal:

Toxicological Sciences

Year:

2018

Language:

english

File:

PDF, 3.90 MB

english, 2018

42

Identification of genomic biomarkers for concurrent diagnosis of drug-induced renal tubular injury using a large-scale toxicogenomics database

Chiaki Kondo, Yohsuke Minowa, Takeki Uehara, Yasushi Okuno, Noriyuki Nakatsu, Atsushi Ono, Toshiyuki Maruyama, Ikuo Kato, Jyoji Yamate, Hiroshi Yamada, Yasuo Ohno, Tetsuro Urushidani

Journal:

Year:

2009

Language:

english

File:

PDF, 790 KB

english, 2009

43

IDENTIFICATION OF GLUTATHIONE DEPLETION-RESPONSIVE GENES USING PHORONE-TREATED RAT LIVER

KIYOSAWA, Naoki, UEHARA, Takeki, GAO, Weihua, OMURA, Ko, HIRODE, Mitsuhiro, SHIMIZU, Toshinobu, MIZUKAWA, Yumiko, ONO, Atsushi, MIYAGISHIMA, Toshikazu, NAGAO, Taku, URUSHIDANI, Tetsuro

Journal:

The Journal of Toxicological Sciences

Year:

2007

Language:

english

File:

PDF, 3.04 MB

english, 2007

44

Evaluation of the usefulness of urinary biomarkers for nephrotoxicity in rats

Yutaka Tonomura, Noriko Tsuchiya, Mikinori Torii, Takeki Uehara

Journal:

Year:

2010

Language:

english

File:

PDF, 1.53 MB

english, 2010

45

Toxicogenomic biomarkers for renal papillary injury in rats

Uehara, Takeki, Kondo, Chiaki, Morikawa, Yuji, Hanafusa, Hiroyuki, Ueda, Seiko, Minowa, Yohsuke, Nakatsu, Noriyuki, Ono, Atsushi, Maruyama, Toshiyuki, Kato, Ikuo, Yamate, Jyoji, Yamada, Hiroshi, Ohno,

Journal:

Year:

2013

Language:

english

File:

PDF, 1.11 MB

english, 2013

46

Susceptibility of Liver Proliferative Lesions in Heterozygous p53 Deficient CBA Mice to Various Carcinogens

UEHARA, Takeki, KASHIDA, Yoko, WATANABE, Takao, YASUHARA, Kazuo, ONODERA, Hiroshi, HIROSE, Masao, MITSUMORI, Kunitoshi

Journal:

Journal of Veterinary Medical Science

Year:

2002

Language:

english

File:

PDF, 138 KB

english, 2002

47

Identification of metabolomic biomarkers for drug-induced acute kidney injury in rats

Uehara, Takeki, Horinouchi, Akira, Morikawa, Yuji, Tonomura, Yutaka, Minami, Keiichi, Ono, Atsushi, Yamate, Jyoji, Yamada, Hiroshi, Ohno, Yasuo, Urushidani, Tetsuro

Journal:

Journal of Applied Toxicology

Year:

2014

Language:

english

File:

PDF, 922 KB

english, 2014

48

Early treatment with baloxavir marboxil in high-risk adolescent and adult outpatients with uncomplicated influenza (CAPSTONE-2): a randomised, placebo-controlled, phase 3 trial

Ison, Michael G, Portsmouth, Simon, Yoshida, Yuki, Shishido, Takao, Mitchener, Melissa, Tsuchiya, Kenji, Uehara, Takeki, Hayden, Frederick G

Journal:

The Lancet Infectious Diseases

Year:

2020

File:

PDF, 394 KB

2020

49

Detection of initiating potential of non-genotoxic carcinogens in a two-stage hepatocarcinogenesis study in rats

Omura, Ko, Uehara, Takeki, Morikawa, Yuji, Hayashi, Hitomi, Mitsumori, Kunitoshi, Minami, Keiichi, Kanki, Masayuki, Yamada, Hiroshi, Ono, Atsushi, Urushidani, Tetsuro

Journal:

The Journal of Toxicological Sciences

Year:

2014

Language:

english

File:

PDF, 2.56 MB

english, 2014

50

Gene expression profiling in rat liver treated with various hepatotoxic-compounds inducing coagulopathy

Hirode, Mitsuhiro, Omura, Ko, Kiyosawa, Naoki, Uehara, Takeki, Shimuzu, Toshinobu, Ono, Atsushi, Miyagishima, Toshikazu, Nagao, Taku, Ohno, Yasuo, Urushidani, Tetsuro

Journal:

The Journal of Toxicological Sciences

Year:

2009

Language:

english

File:

PDF, 361 KB

english, 2009

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